Ergogenics   [Definitie:] "An ergogenic aid is any substance or phenomenon that enhances performance." (Wilmore and Costill)   Nieuwsbrief over doping, supplementen, voeding en training
Myostatinblokkers JA16 / MYO029       Batimastat       ACVR2B       ACE-031

Effects of an alleged myostatin-binding supplement and heavy resistance training on serum myostatin, muscle strength and mass, and body composition Willoughby DS. Exercise and Biochemical Nutrition Laboratory, Dept of Health, Human Performance, and Recreation, Baylor University, Waco, TX 76798-7313, USA Int J Sport Nutr Exerc Metab. 2004 Aug;14(4):461-72. This study examined 12 wk of resistance training and cystoseira canariensis [ErGs] supplementation on serum levels of myostatin and follistatin-like related gene (FLRG) and muscle strength and body composition. Twenty-two untrained males were randomly assigned to a placebo (PLC) or myostatin binder (MYO) group in a double-blind fashion. Blood was obtained before and after 6 and 12 wk of training. PLC and MYO trained thrice weekly using 3 sets of 6 to 8 repetitions at 85 % to 90 % 1 repetition maximum. MYO ingested 1200 mg/d of cystoseira canariensis. Data were analyzed with 2-way ANOVA. After training, total body mass, fat-free mass, muscle strength, thigh volume/mass, and serum myostatin and FLRG increased for both groups (P < 0.05); however, there were no differences between groups (P > 0.05). Twelve wk of heavy resistance training and 1200 mg/d of cystoseira canariensis supplementation appears ineffective at inhibiting serum myostatin and increasing muscle strength and mass or decreasing fat mass. [PMID: 15467103]

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